Soluble and Exosome-Bound α-Galactosylceramide Mediate Preferential Proliferation of Educated NK Cells with Increased Anti-Tumor Capacity

SIMPLE SUMMARY: Many cancers down-regulate the expression of major histocompatibility complex class I (MHC-I) to avoid recognition and elimination by the adaptive immune system. Natural Killer (NK) cells, as part of innate immunity, complement tumor recognition by their ability to sense foreign and...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Wagner, Arnika K., Gehrmann, Ulf, Hiltbrunner, Stefanie, Carannante, Valentina, Luu, Thuy T., Näslund, Tanja I., Brauner, Hanna, Kadri, Nadir, Kärre, Klas, Gabrielsson, Susanne
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7830699/
https://ncbi.nlm.nih.gov/pubmed/33467442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020298
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