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Inhibition of Orexin/Hypocretin Neurons Ameliorates Elevated Physical Activity and Energy Expenditure in the A53T Mouse Model of Parkinson’s Disease

Aside from the classical motor symptoms, Parkinson’s disease also has various non-classical symptoms. Interestingly, orexin neurons, involved in the regulation of exploratory locomotion, spontaneous physical activity, and energy expenditure, are affected in Parkinson’s. In this study, we hypothesize...

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Pubblicato in:Int J Mol Sci
Autori principali: Stanojlovic, Milos, Pallais, Jean Pierre, Kotz, Catherine M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7830608/
https://ncbi.nlm.nih.gov/pubmed/33466831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020795
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