Enhanced DNA Repair Pathway is Associated with Cell Proliferation and Worse Survival in Hepatocellular Carcinoma (HCC)

SIMPLE SUMMARY: We studied the relationship between enhancement of DNA repair and cancer aggressiveness, tumor immune microenvironment, and patient survival in 749 hepatocellular carcinoma (HCC) patients from 5 cohorts using a DNA repair pathway score. We show that the DNA repair pathway was enhance...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Oshi, Masanori, Kim, Tae Hee, Tokumaru, Yoshihisa, Yan, Li, Matsuyama, Ryusei, Endo, Itaru, Cherkassky, Leonid, Takabe, Kazuaki
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7830462/
https://ncbi.nlm.nih.gov/pubmed/33477315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020323
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