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Emerging Roles of Protease-Activated Receptors (PARs) in the Modulation of Synaptic Transmission and Plasticity

Protease-activated receptors (PARs) are a class of G protein-coupled receptors (GPCRs) with a unique mechanism of activation, prompted by a proteolytic cleavage in their N-terminal domain that uncovers a tethered ligand, which binds and stimulates the same receptor. PARs subtypes (PAR1-4) have well-...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Price, Rachel, Mercuri, Nicola Biagio, Ledonne, Ada
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7830300/
https://ncbi.nlm.nih.gov/pubmed/33467143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020869
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