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EZH1/2 Inhibitors Favor ILC3 Development from Human HSPC-CD34(+) Cells

SIMPLE SUMMARY: It has been well-demonstrated that EZH1/2 enzymes are involved not only in tumor development and progression, but also in the regulation of normal hematopoiesis from CD34(+)-HSPC. Given the crucial role of NK cells in tumor immune surveillance, in this study, we investigated whether...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Damele, Laura, Amaro, Adriana, Serio, Alberto, Luchetti, Silvia, Pfeffer, Ulrich, Mingari, Maria Cristina, Vitale, Chiara
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7830003/
https://ncbi.nlm.nih.gov/pubmed/33467134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020319
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