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Astragalin Alleviates Neuropathic Pain by Suppressing P2X4-Mediated Signaling in the Dorsal Root Ganglia of Rats

Neurologic damage often leads to neuropathic pain, for which there are no effective treatments owing to its complex pathogenesis. The purinergic receptor P2X4 is closely associated with neuropathic pain. Astragalin (AST), a compound that is used in traditional Chinese medicine, has protective effect...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Neurosci
Hauptverfasser: Wang, Mengke, Cai, Xia, Wang, Yueying, Li, Shizhen, Wang, Na, Sun, Rui, Xing, Jingming, Liang, Shangdong, Liu, Shuangmei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7829479/
https://ncbi.nlm.nih.gov/pubmed/33505232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.570831
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