Targeting TRPV1-mediated autophagy attenuates nitrogen mustard-induced dermal toxicity

Nitrogen mustard (NM) causes severe vesicating skin injury, which lacks effective targeted therapies. The major limitation is that the specific mechanism of NM-induced skin injury is not well understood. Recently, autophagy has been found to play important roles in physical and chemical exposure-cau...

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Bibliografske podrobnosti
izdano v:Signal Transduct Target Ther
Main Authors: Chen, Mingliang, Dong, Xunhu, Deng, Haoyue, Ye, Feng, Zhao, Yuanpeng, Cheng, Jin, Dan, Guorong, Zhao, Jiqing, Sai, Yan, Bian, Xiuwu, Zou, Zhongmin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7829253/
https://ncbi.nlm.nih.gov/pubmed/33487631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-00389-z
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