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Progesterone's Effects on Cognitive Performance of Male Mice Are Independent of Progestin Receptors but Relate to Increases in GABA(A) Activity in the Hippocampus and Cortex

Progestogens' (e.g., progesterone and its neuroactive metabolite, allopregnanolone), cognitive effects and mechanisms among males are not well-understood. We hypothesized if progestogen's effects on cognitive performance are through its metabolite allopregnanolone, and not actions via bind...

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Vydáno v:Front Endocrinol (Lausanne)
Hlavní autoři: Frye, Cheryl A., Lembo, Vincent F., Walf, Alicia A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7829189/
https://ncbi.nlm.nih.gov/pubmed/33505354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.552805
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