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Macrophage-Derived Inflammation Induces a Transcriptome Makeover in Mesenchymal Stromal Cells Enhancing Their Potential for Tissue Repair

Pre-clinical and clinical studies revealed that mesenchymal stromal cell (MSC) transplants elicit tissue repair. Conditioning MSC prior to transplantation may boost their ability to support repair. We investigated macrophage-derived inflammation as a means to condition MSC by comprehensively analyzi...

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Publicat a:Int J Mol Sci
Autors principals: Maldonado-Lasunción, Inés, O’Neill, Nick, Umland, Oliver, Verhaagen, Joost, Oudega, Martin
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828776/
https://ncbi.nlm.nih.gov/pubmed/33466704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020781
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