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Anti-Warburg Effect of Melatonin: A Proposed Mechanism to Explain its Inhibition of Multiple Diseases

Glucose is an essential nutrient for every cell but its metabolic fate depends on cellular phenotype. Normally, the product of cytosolic glycolysis, pyruvate, is transported into mitochondria and irreversibly converted to acetyl coenzyme A by pyruvate dehydrogenase complex (PDC). In some pathologica...

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Pubblicato in:Int J Mol Sci
Autori principali: Reiter, Russel J., Sharma, Ramaswamy, Rosales-Corral, Sergio
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828708/
https://ncbi.nlm.nih.gov/pubmed/33466614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020764
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