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Anti-Warburg Effect of Melatonin: A Proposed Mechanism to Explain its Inhibition of Multiple Diseases

Glucose is an essential nutrient for every cell but its metabolic fate depends on cellular phenotype. Normally, the product of cytosolic glycolysis, pyruvate, is transported into mitochondria and irreversibly converted to acetyl coenzyme A by pyruvate dehydrogenase complex (PDC). In some pathologica...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Reiter, Russel J., Sharma, Ramaswamy, Rosales-Corral, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828708/
https://ncbi.nlm.nih.gov/pubmed/33466614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020764
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