Anti-Warburg Effect of Melatonin: A Proposed Mechanism to Explain its Inhibition of Multiple Diseases

Glucose is an essential nutrient for every cell but its metabolic fate depends on cellular phenotype. Normally, the product of cytosolic glycolysis, pyruvate, is transported into mitochondria and irreversibly converted to acetyl coenzyme A by pyruvate dehydrogenase complex (PDC). In some pathologica...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Reiter, Russel J., Sharma, Ramaswamy, Rosales-Corral, Sergio
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828708/
https://ncbi.nlm.nih.gov/pubmed/33466614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020764
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