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Anti-Warburg Effect of Melatonin: A Proposed Mechanism to Explain its Inhibition of Multiple Diseases

Glucose is an essential nutrient for every cell but its metabolic fate depends on cellular phenotype. Normally, the product of cytosolic glycolysis, pyruvate, is transported into mitochondria and irreversibly converted to acetyl coenzyme A by pyruvate dehydrogenase complex (PDC). In some pathologica...

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Podrobná bibliografie
Vydáno v:Int J Mol Sci
Hlavní autoři: Reiter, Russel J., Sharma, Ramaswamy, Rosales-Corral, Sergio
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828708/
https://ncbi.nlm.nih.gov/pubmed/33466614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020764
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