The Taming of Nuclear Factor Erythroid-2-Related Factor-2 (Nrf2) Deglycation by Fructosamine-3-Kinase (FN3K)-Inhibitors-A Novel Strategy to Combat Cancers

SIMPLE SUMMARY: Aim of this review is to provide an overview on (a) Fructosamine-3-Kinase (FN3K) and its role in regulating Nuclear Factor Erythorid-2-Related Factor-2 (Nrf2); (b) the role of glycation and deglycation mechanisms in modulating the functional properties of proteins, in particular, the...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Beeraka, Narasimha M., Bovilla, Venugopal R., Doreswamy, Shalini H., Puttalingaiah, Sujatha, Srinivasan, Asha, Madhunapantula, SubbaRao V.
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828646/
https://ncbi.nlm.nih.gov/pubmed/33466626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020281
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