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High-Content Screening for the Detection of Drug-Induced Oxidative Stress in Liver Cells

Drug-induced liver injury (DILI) remains a major cause of drug development failure, post-marketing warnings and restriction of use. An improved understanding of the mechanisms underlying DILI is required for better drug design and development. Enhanced reactive oxygen species (ROS) levels may cause...

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Dettagli Bibliografici
Pubblicato in:Antioxidants (Basel)
Autori principali: Donato, María Teresa, Tolosa, Laia
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828515/
https://ncbi.nlm.nih.gov/pubmed/33451093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10010106
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