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A Perspective on Natural and Nature-Inspired Small Molecules Targeting Phosphodiesterase 9 (PDE9): Chances and Challenges against Neurodegeneration

As life expectancy increases, dementia affects a growing number of people worldwide. Besides current treatments, phosphodiesterase 9 (PDE9) represents an alternative target for developing innovative small molecules to contrast neurodegeneration. PDE inhibition promotes neurotransmitter release, amel...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Ribaudo, Giovanni, Memo, Maurizio, Gianoncelli, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828511/
https://ncbi.nlm.nih.gov/pubmed/33451065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14010058
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