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Hindering triple negative breast cancer progression by targeting endogenous interleukin‐30 requires IFNγ signaling

IL30mRNA expression is associated with the TNBC subtype. IL30 boosts proliferation and migration of TNBC cells and reshapes their immunity gene expression profile. The lack of endogenous IL30 hinders TNBC growth and progression and prolongs host survival. TNBC growth inhibition, due to the lack of e...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Transl Med
Hauptverfasser: Sorrentino, Carlo, Ciummo, Stefania Livia, D'Antonio, Luigi, Lanuti, Paola, Abrams, Scott I., Yin, Zhinan, Lu, Li‐Fan, Di Carlo, Emma
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828256/
https://ncbi.nlm.nih.gov/pubmed/33635005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.278
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