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Elevated Expression of Cathepsin K in Periodontal Ligament Fibroblast by Inflammatory Cytokines Accelerates Osteoclastogenesis via Paracrine Mechanism in Periodontal Disease

Cathepsin K (CTSK) is a cysteine protease that is mainly produced from mature osteoclasts and contributes to the destruction of connective tissues and mineralized matrix as a consequence of periodontal disease (PD). However, few studies have reported its regulatory role in osteoclastogenesis-support...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Heo, Soon Chul, Kim, Yu Na, Choi, YunJeong, Joo, Ji-Young, Hwang, Jae Joon, Bae, Moon-Kyoung, Kim, Hyung Joon
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828200/
https://ncbi.nlm.nih.gov/pubmed/33445732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020695
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