Activation of an Effective Immune Response after Yellow Fever Vaccination Is Associated with the Genetic Background and Early Response of IFN-γ and CLEC5A

The yellow fever vaccine (YF17DD) is highly effective with a single injection conferring protection for at least 10 years. The YF17DD induces polyvalent responses, with a TH1/TH2 CD4(+) profile, robust T CD8(+) responses, and synthesis of interferon-gamma (IFN-γ), culminating in high titers of neutr...

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Udgivet i:Viruses
Main Authors: Azamor, Tamiris, da Silva, Andréa Marques Vieira, Melgaço, Juliana Gil, dos Santos, Ana Paula, Xavier-Carvalho, Caroline, Alvarado-Arnez, Lucia Elena, Batista-Silva, Leonardo Ribeiro, de Souza Matos, Denise Cristina, Bayma, Camilla, Missailidis, Sotiris, Ano Bom, Ana Paula Dinis, Moraes, Milton Ozorio, da Costa Neves, Patrícia Cristina
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828179/
https://ncbi.nlm.nih.gov/pubmed/33445752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13010096
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