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Chemotherapy-Induced Upregulation of Somatostatin Receptor-2 Increases the Uptake and Efficacy of (177)Lu-DOTA-Octreotate in Neuroendocrine Tumor Cells

SIMPLE SUMMARY: The peptide receptor radionuclide therapy (PRRT) with (177)Lu-DOTA-octreotate (LuTate) is recommended for neuroendocrine tumors (NETs) which overexpress somatostatin receptors (SSTR). A combination of LuTate with chemotherapy improves its objective response in NET patients, and here...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Shah, Rashmi G., Merlin, Marine A., Adant, Samuel, Zine-Eddine, Fayçal, Beauregard, Jean-Mathieu, Shah, Girish M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828052/
https://ncbi.nlm.nih.gov/pubmed/33435224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020232
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