Splenectomy Prior to Experimental Induction of Autoimmune Hepatitis Promotes More Severe Hepatic Inflammation, Production of IL-17 and Apoptosis

Autoimmune hepatitis (AIH) is detected at a late stage in the course of the disease. Therefore, induction and etiology are largely unclear. It is controversial if the induction of autoimmunity occurs in the liver or in the spleen. In our experimental murine AIH model, the induction of autoimmunity d...

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Bibliografiske detaljer
Udgivet i:Biomedicines
Main Authors: Buitrago-Molina, Laura Elisa, Dywicki, Janine, Noyan, Fatih, Trippler, Martin, Pietrek, Julia, Schlue, Jerome, Manns, Michael P., Wedemeyer, Heiner, Jaeckel, Elmar, Hardtke-Wolenski, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7827897/
https://ncbi.nlm.nih.gov/pubmed/33435354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9010058
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