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Mechanisms of Insulin Resistance at the Crossroad of Obesity with Associated Metabolic Abnormalities and Cognitive Dysfunction

Obesity mediates most of its direct medical sequelae through the development of insulin resistance (IR). The cellular effects of insulin occur through two main postreceptor pathways that are the phosphatidylinositol 3-kinase (PI3-K) and the mitogen-activated protein kinase (MAP-K) pathways. Obesity-...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Barber, Thomas M., Kyrou, Ioannis, Randeva, Harpal S., Weickert, Martin O.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7827338/
https://ncbi.nlm.nih.gov/pubmed/33430419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020546
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