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Topical TRPM8 Agonist for Relieving Neuropathic Ocular Pain in Patients with Dry Eye: A Pilot Study

Background: Activation of TRPM8, a cold-sensing receptor located on the cornea and eyelid, has the potential to relieve the neuropathic ocular pain (NOP) in dry eye (DE) by inhibiting other aberrant nociceptive inputs. We aimed to investigate the effect of a topical TRPM8 agonist, cryosim-3 (C3), on...

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Bibliografske podrobnosti
izdano v:J Clin Med
Main Authors: Yoon, Hyeon Jeong, Kim, Jonghwa, Yang, Jee Myung, Wei, Edward T., Kim, Seong Jin, Yoon, Kyung Chul
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826705/
https://ncbi.nlm.nih.gov/pubmed/33445485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10020250
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