Nuclear Localization of PTTG1 Promotes Migration and Invasion of Seminoma Tumor through Activation of MMP-2

SIMPLE SUMMARY: Seminoma is the most common subtype of testicular germ cell tumors (TGCTs) and its molecular patterns have not been clarified. The pituitary tumor-transforming gene 1 (PTTG1) is a securin and its overexpression is reported in many cancers. We previously demonstrated that PTTG1 is mai...

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Publicado en:Cancers (Basel)
Main Authors: Teveroni, Emanuela, Di Nicuolo, Fiorella, Bianchetti, Giada, Epstein, Alan L., Grande, Giuseppe, Maulucci, Giuseppe, De Spirito, Marco, Pontecorvi, Alfredo, Milardi, Domenico, Mancini, Francesca
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826632/
https://ncbi.nlm.nih.gov/pubmed/33430117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020212
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