Cyclodextrin Diethyldithiocarbamate Copper II Inclusion Complexes: A Promising Chemotherapeutic Delivery System against Chemoresistant Triple Negative Breast Cancer Cell Lines

Diethyldithiocarbamate Copper II (DDC-Cu) has shown potent anticancer activity against a wide range of cancer cells, but further investigations are hindered by its practical insolubility in water. In this study, inclusion complexes of DDC-Cu with hydroxypropyl beta-cyclodextrin (HP) or sulfobutyl et...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Said Suliman, Ammar, Khoder, Mouhamad, Tolaymat, Ibrahim, Webster, Matt, Alany, Raid G., Wang, Weiguang, Elhissi, Abdelbary, Najlah, Mohammad
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826515/
https://ncbi.nlm.nih.gov/pubmed/33435151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13010084
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