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Placental trophoblast syncytialization potentiates macropinocytosis via mTOR signaling to adapt to reduced amino acid supply

During pregnancy, the appropriate allocation of nutrients between the mother and the fetus is dominated by maternal–fetal interactions, which is primarily governed by the placenta. The syncytiotrophoblast (STB) lining at the outer surface of the placental villi is directly bathed in maternal blood a...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Shao, Xuan, Cao, Guangming, Chen, Dunjin, Liu, Juan, Yu, Bolan, Liu, Ming, Li, Yu-Xia, Cao, Bin, Sadovsky, Yoel, Wang, Yan-Ling
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826386/
https://ncbi.nlm.nih.gov/pubmed/33402432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017092118
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