Penetration of Flurbiprofen from a Locally Applied Sore Throat Lozenge and Spray into Cadaveric Human Pharynx Tissue: A Novel ex vivo Model and Microautoradiography Method

OBJECTIVE: Flurbiprofen 8.75 mg lozenge and spray are used for symptomatic relief of sore throat, with a rapid onset of analgesia suggesting a localized mechanism of action. Building on previous studies, this investigation aimed to use microautoradiography to visualize the depth penetration of radio...

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Veröffentlicht in:Clin Pharmacol
Hauptverfasser: Turner, Rob, Wevrett, Sean Robert, Edmunds, Suzanne, Brown, Marc, Kulasekaran, Anuradha, Adegoke, Oluwajoba, Farrah, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2021
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826073/
https://ncbi.nlm.nih.gov/pubmed/33500668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S284433
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