Pharmacoinformatics approach based identification of potential Nsp15 endoribonuclease modulators for SARS-CoV-2 inhibition

In the current study, a structure-based virtual screening paradigm was used to screen a small molecular database against the Non-structural protein 15 (Nsp15) endoribonuclease of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 is the causative agent of the recent outbrea...

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Vydáno v:Arch Biochem Biophys
Hlavní autoři: Savale, Rutuja Umesh, Bhowmick, Shovonlal, Osman, Sameh Mohamed, Alasmary, Fatmah Ali, Almutairi, Tahani Mazyad, Abdullah, Dalal Saied, Patil, Pritee Chunarkar, Islam, Md Ataul
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Inc. 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7825923/
https://ncbi.nlm.nih.gov/pubmed/33485847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2021.108771
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