Altered TGFβ/SMAD Signaling in Human and Rat Models of Pulmonary Hypertension: An Old Target Needs Attention

Recent translational studies highlighted the inhibition of transforming growth factor (TGF)-β signaling as a promising target to treat pulmonary arterial hypertension (PAH). However, it remains unclear whether alterations in TGF-β signaling are consistent between PAH patients and animal models. Ther...

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Vydáno v:Cells
Hlavní autoři: Sanada, Takayuki Jujo, Sun, Xiao-Qing, Happé, Chris, Guignabert, Christophe, Tu, Ly, Schalij, Ingrid, Bogaard, Harm-Jan, Goumans, Marie-José, Kurakula, Kondababu
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7825543/
https://ncbi.nlm.nih.gov/pubmed/33419137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10010084
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