Experimental dopaminergic neuron lesion at the area of the biological clock pacemaker, suprachiasmatic nuclei (SCN) induces metabolic syndrome in rats

BACKGROUND: The daily peak in dopaminergic neuronal activity at the area of the biological clock (hypothalamic suprachiasmatic nuclei [SCN]) is diminished in obese/insulin resistant vs lean/insulin sensitive animals. The impact of targeted lesioning of dopamine (DA) neurons specifically at the area...

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Detalhes bibliográficos
Publicado no:Diabetol Metab Syndr
Main Authors: Luo, Shuqin, Ezrokhi, Michael, Cominos, Nicholas, Tsai, Tsung-Huang, Stoelzel, Carl R., Trubitsyna, Yelena, Cincotta, Anthony H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7825247/
https://ncbi.nlm.nih.gov/pubmed/33485386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13098-021-00630-x
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