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Hypoxic tumour cell-derived exosomal miR-340-5p promotes radioresistance of oesophageal squamous cell carcinoma via KLF10

BACKGROUND: Radiotherapy resistance is a major obstacle in the treatment of oesophageal squamous cell carcinoma (OSCC). Hypoxia is a critical cause of radioresistance. However, the communication between hypoxic cells and aerobic cells via exosomes during the transfer of radiation resistance remains...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Chen, Fangyu, Xu, Bing, Li, Jie, Yang, Xi, Gu, Junjie, Yao, Xijuan, Sun, Xinchen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7825246/
https://ncbi.nlm.nih.gov/pubmed/33485367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01834-9
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