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HELQ and EGR3 expression correlate with IGHV mutation status and prognosis in chronic lymphocytic leukemia

BACKGROUND: IGHV mutation status is a crucial prognostic biomarker for CLL. In the present study, we investigated the transcriptomic signatures associating with IGHV mutation status and CLL prognosis. METHODS: The co-expression modules and hub genes correlating with IGHV status, were identified usin...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Guo, Chao, Gao, Ya-yue, Ju, Qian-qian, Zhang, Chun-xia, Gong, Ming, Li, Zhen-ling
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7825181/
https://ncbi.nlm.nih.gov/pubmed/33485349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02708-6
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