Pathologically Decreased CSF Levels of Synaptic Marker NPTX2 in DLB Are Correlated with Levels of Alpha-Synuclein and VGF

Background: Dementia with Lewy bodies (DLB) is a neurodegenerative disease where synaptic loss and reduced synaptic integrity are important neuropathological substrates. Neuronal Pentraxin 2(NPTX2) is a synaptic protein that drives the GABAergic inhibitory circuit. Our aim was to examine if NPTX2 ce...

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Publicado no:Cells
Main Authors: Boiten, Walter A., van Steenoven, Inger, Xiao, Mei-Fang, Worley, Paul F., Noli, Barbara, Cocco, Cristina, Ferri, Gian-Luca, Lemstra, Afina W., Teunissen, Charlotte E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7824459/
https://ncbi.nlm.nih.gov/pubmed/33383752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10010038
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