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The PIKfyve Inhibitor Apilimod: A Double-Edged Sword against COVID-19

The PIKfyve inhibitor apilimod is currently undergoing clinical trials for treatment of COVID-19. However, although apilimod might prevent viral invasion by inhibiting host cell proteases, the same proteases are critical for antigen presentation leading to T cell activation and there is good evidenc...

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Vydáno v:Cells
Hlavní autoři: Baranov, Maksim V., Bianchi, Frans, van den Bogaart, Geert
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7824419/
https://ncbi.nlm.nih.gov/pubmed/33375410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10010030
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