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The PIKfyve Inhibitor Apilimod: A Double-Edged Sword against COVID-19

The PIKfyve inhibitor apilimod is currently undergoing clinical trials for treatment of COVID-19. However, although apilimod might prevent viral invasion by inhibiting host cell proteases, the same proteases are critical for antigen presentation leading to T cell activation and there is good evidenc...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Baranov, Maksim V., Bianchi, Frans, van den Bogaart, Geert
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7824419/
https://ncbi.nlm.nih.gov/pubmed/33375410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10010030
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