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A Screen for Small Molecules to Target Candida albicans Biofilms

The human fungal pathogen Candida albicans can form biofilms on biotic and abiotic surfaces, which are inherently resistant to antifungal drugs. We screened the Chembridge Small Molecule Diversity library containing 30,000 “drug-like” small molecules and identified 45 compounds that inhibited biofil...

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Detalhes bibliográficos
Publicado no:J Fungi (Basel)
Main Authors: Lohse, Matthew B., Ennis, Craig L., Hartooni, Nairi, Johnson, Alexander D., Nobile, Clarissa J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7824004/
https://ncbi.nlm.nih.gov/pubmed/33375490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jof7010009
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