Effect of Diphenyleneiodonium Chloride on Intracellular Reactive Oxygen Species Metabolism with Emphasis on NADPH Oxidase and Mitochondria in Two Therapeutically Relevant Human Cell Types

Reactive oxygen species (ROS) have recently been recognized as important signal transducers, particularly regulating proliferation and differentiation of cells. Diphenyleneiodonium (DPI) is known as an inhibitor of the nicotinamide adenine dinucleotide phosphate oxidase (NOX) and is also affecting m...

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Publicado en:Pharmaceutics
Autores principales: Zavadskis, Sergejs, Weidinger, Adelheid, Hanetseder, Dominik, Banerjee, Asmita, Schneider, Cornelia, Wolbank, Susanne, Marolt Presen, Darja, Kozlov, Andrey V.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7823933/
https://ncbi.nlm.nih.gov/pubmed/33374729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13010010
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