Dual GIP and GLP-1 Receptor Agonist Tirzepatide Improves Beta-cell Function and Insulin Sensitivity in Type 2 Diabetes

CONTEXT: Novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist (RA) tirzepatide demonstrated substantially greater glucose control and weight loss (WL) compared with selective GLP-1RA dulaglutide. OBJECTIVE: Explore mechanisms of glucose c...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Thomas, Melissa K, Nikooienejad, Amir, Bray, Ross, Cui, Xuewei, Wilson, Jonathan, Duffin, Kevin, Milicevic, Zvonko, Haupt, Axel, Robins, Deborah A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7823251/
https://ncbi.nlm.nih.gov/pubmed/33236115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgaa863
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