Galanin promotes autophagy and alleviates apoptosis in the hypertrophied heart through FoxO1 pathway

Autophagy and apoptosis are powerful regulators of multiple facets of cellular metabolism and homeostasis. Here, we uncover that galanin, a pleiotropic peptide, regulates cardiac autophagy and deactivates apoptotic cell death through the Forkhead box protein O1 (FoxO1) pathway. In hypertrophied hear...

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Dades bibliogràfiques
Publicat a:Redox Biol
Autors principals: Martinelli, Ilenia, Timotin, Andrei, Moreno-Corchado, Paula, Marsal, Dimitri, Kramar, Solomiia, Loy, Halina, Joffre, Carine, Boal, Frederic, Tronchere, Helene, Kunduzova, Oksana
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7823211/
https://ncbi.nlm.nih.gov/pubmed/33493902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101866
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