Cell-penetrating, antioxidant SELENOT mimetic protects dopaminergic neurons and ameliorates motor dysfunction in Parkinson's disease animal models

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor dysfunction for which there is an unmet need for better treatment options. Although oxidative stress is a common feature of neurodegenerative diseases, notably PD, there is currently no efficient therapeutic strateg...

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Vydáno v:Redox Biol
Hlavní autoři: Alsharif, Ifat, Boukhzar, Loubna, Lefranc, Benjamin, Godefroy, David, Aury-Landas, Juliette, Rego, Jean-Luc do, Rego, Jean-Claude do, Naudet, Frédéric, Arabo, Arnaud, Chagraoui, Abdeslam, Maltête, David, Benazzouz, Abdelhamid, Baugé, Catherine, Leprince, Jérôme, Elkahloun, Abdel G., Eiden, Lee E., Anouar, Youssef
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7823055/
https://ncbi.nlm.nih.gov/pubmed/33486153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101839
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