Adipose tissue–derived stem cells protect the primordial follicle pool from both direct follicle death and abnormal activation after ovarian tissue transplantation

PURPOSE: To investigate whether adipose tissue–derived stem cells (ASCs) protect the primordial follicle pool, not only by decreasing direct follicle loss but also by modulating follicle activation pathways. METHODS: Twenty nude mice were grafted with frozen-thawed human ovarian tissue from 5 patien...

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Vydáno v:J Assist Reprod Genet
Hlavní autoři: Cacciottola, Luciana, Courtoy, Guillaume E., Nguyen, Thu Y. T., Hossay, Camille, Donnez, Jacques, Dolmans, Marie-Madeleine
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2020
Témata:
Reproductive Physiology and Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7823002/
https://ncbi.nlm.nih.gov/pubmed/33184773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-020-02005-z
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