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A theoretical and generalized approach for the assessment of the sample-specific limit of detection for clinical metagenomics

Metagenomics is a powerful tool to identify novel or unexpected pathogens, since it is generic and relatively unbiased. The limit of detection (LOD) is a critical parameter for the routine application of methods in the clinical diagnostic context. Although attempts for the determination of LODs for...

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Publicat a:Comput Struct Biotechnol J
Autors principals: Ebinger, Arnt, Fischer, Susanne, Höper, Dirk
Format: Artigo
Idioma:Inglês
Publicat: Research Network of Computational and Structural Biotechnology 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822954/
https://ncbi.nlm.nih.gov/pubmed/33552445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.12.040
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