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Deubiquitylating enzymes in neuronal health and disease

Ubiquitylation and deubiquitylation play a pivotal role in protein homeostasis (proteostasis). Proteostasis shapes the proteome landscape in the human brain and its impairment is linked to neurodevelopmental and neurodegenerative disorders. Here we discuss the emerging roles of deubiquitylating enzy...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Amer-Sarsour, Fatima, Kordonsky, Alina, Berdichevsky, Yevgeny, Prag, Gali, Ashkenazi, Avraham
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822931/
https://ncbi.nlm.nih.gov/pubmed/33483467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03361-5
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