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Molecular pathology associated with altered synaptic transcriptome in the dorsolateral prefrontal cortex of depressed subjects

Disrupted synaptic plasticity is the hallmark of major depressive disorder (MDD), with accompanying changes at the molecular and cellular levels. Often, the maladaptive molecular changes at the synapse are the result of global transcriptional reprogramming dictated by activity-dependent synaptic mod...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Yoshino, Yuta, Roy, Bhaskar, Kumar, Nilesh, Shahid Mukhtar, M., Dwivedi, Yogesh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822869/
https://ncbi.nlm.nih.gov/pubmed/33483466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-01159-9
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