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Sequential Water and Headgroup Merger: Membrane Poration Paths and Energetics from MD Simulations

Membrane topology changes such as poration, stalk formation, and hemifusion rupture are essential to cellular function, but their molecular details, energetics, and kinetics are still not fully understood. Here, we present a unified energetic and mechanistic picture of metastable pore defects in ten...

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Bibliografiset tiedot
Julkaisussa:Biophys J
Päätekijät: Bubnis, Greg, Grubmüller, Helmut
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Biophysical Society 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822740/
https://ncbi.nlm.nih.gov/pubmed/33189685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.10.037
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