Crowding in the Eye Lens: Modeling the Multisubunit Protein β-Crystallin with a Colloidal Approach

We present a multiscale characterization of aqueous solutions of the bovine eye lens protein β(H) crystallin from dilute conditions up to dynamical arrest, combining dynamic light scattering, small-angle x-ray scattering, tracer-based microrheology, and neutron spin echo spectroscopy. We obtain a co...

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Bibliographic Details
Published in:Biophys J
Main Authors: Roosen-Runge, Felix, Gulotta, Alessandro, Bucciarelli, Saskia, Casal-Dujat, Lucía, Garting, Tommy, Skar-Gislinge, Nicholas, Obiols-Rabasa, Marc, Farago, Bela, Zaccarelli, Emanuela, Schurtenberger, Peter, Stradner, Anna
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822730/
https://ncbi.nlm.nih.gov/pubmed/33189682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.10.035
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