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Repurposing the McoTI-II Rigid Molecular Scaffold in to Inhibitor of ‘Papain Superfamily’ Cysteine Proteases

Clan C1A or ‘papain superfamily’ cysteine proteases are key players in many important physiological processes and diseases in most living systems. Novel approaches towards the development of their inhibitors can open new avenues in translational medicine. Here, we report a novel design of a re-engin...

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Bibliographic Details
Published in:Pharmaceuticals (Basel)
Main Authors: Mishra, Manasi, Singh, Vigyasa, Tellis, Meenakshi B., Joshi, Rakesh S., Singh, Shailja
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822474/
https://ncbi.nlm.nih.gov/pubmed/33374547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14010007
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