Foot-and-Mouth Disease Virus Capsid Protein VP1 Antagonizes TPL2-Mediated Activation of the IRF3/IFN-β Signaling Pathway to Facilitate the Virus Replication

Foot-and-mouth disease (FMD) is a severe, highly contagious viral disease of cloven-hoofed animals. In order to establish an infection, the FMD virus (FMDV) needs to counteract host antiviral responses. Tumor progression locus 2 (TPL2), a mitogen-activated protein kinase, can regulate innate and ada...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hao, Junhong, Shen, Chaochao, Wei, Nannan, Yan, Minghao, Zhang, Xuegang, Xu, Guowei, Zhang, Dajun, Hou, Jing, Cao, Weijun, Jin, Ye, Zhang, Keshan, Zheng, Haixue, Liu, Xiangtao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821752/
https://ncbi.nlm.nih.gov/pubmed/33488582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.580334
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