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Sex-specific epigenetic profile of inner cell mass of mice conceived in vivo or by IVF

The preimplantation stage of development is exquisitely sensitive to environmental stresses, and changes occurring during this developmental phase may have long-term health effects. Animal studies indicate that IVF offspring display metabolic alterations, including hypertension, glucose intolerance...

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Publicado en:Mol Hum Reprod
Main Authors: Ruggeri, Elena, Lira-Albarrán, Saúl, Grow, Edward J, Liu, Xiaowei, Harner, Royce, Maltepe, Emin, Ramalho-Santos, Miguel, Donjacour, Annemarie, Rinaudo, Paolo
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821709/
https://ncbi.nlm.nih.gov/pubmed/33010164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gaaa064
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