The Molecular Landscape and Biological Alterations Induced by PRAS40-Knockout in Head and Neck Squamous Cell Carcinoma

PRAS40 (Prolin-rich Akt substrate of 40 kDa) is a critical protein, which directly connects PI3K/Akt and mTORC1 pathway. It plays an indispensable role in the development of various diseases. However, the relationship between PRAS40 and head and neck squamous cell carcinoma (HNSCC) remains unclear....

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Oncol
Main Authors: Chen, Gang, Li, Zhexuan, Chen, Changhan, Liu, Jiajia, Zhu, Weiming, She, Li, Huang, Huimei, Qin, Yuexiang, Liu, Guancheng, Wang, Juncheng, Liu, Yong, Huang, Donghai, Tang, Qinglai, Zhang, Xin, Zhu, Gangcai
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Oncology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821427/
https://ncbi.nlm.nih.gov/pubmed/33489877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.565669
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