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Probing the Conformation States of Neurotensin Receptor 1 Variants by NMR Site‐Directed Methyl Labeling

G protein‐coupled receptors (GPCRs) are key players in mediating signal transduction across the cell membrane. However, due to their intrinsic instability, many GPCRs are not suitable for structural investigations. Various approaches have been developed in recent years to remedy this situation, rang...

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Détails bibliographiques
Publié dans:Chembiochem
Auteurs principaux: Goba, Inguna, Goricanec, David, Schum, Dominik, Hillenbrand, Matthias, Plückthun, Andreas, Hagn, Franz
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821118/
https://ncbi.nlm.nih.gov/pubmed/32881260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000541
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